SEVERO GOMES, ANTONIEL AUGUSTO ; DE CASTRO NASCIMENTO DE SOUZA, ANA CAROLINE ; BARBOSA LEITE, ARIELY ; SILVIO MORETTI, NILMAR ; ROBERTO DE MATTOS FONTES, MARCOS ; Schenkman, Sergio . Effect of lysine acetylation on the regulation of Trypanosoma brucei glycosomal aldolase activity. BIOCHEMICAL JOURNAL, v. 477, p. 1733-1744, 2020.
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NUNES, VINICIUS SANTANA ; MORETTI, NILMAR SILVIO ; DA SILVA, MARCELO SANTOS ; Elias, Maria Carolina ; JANZEN, CHRISTIAN J. ; Schenkman, Sergio . Trimethylation of histone H3K76 by Dot1B enhances cell cycle progression after mitosis in Trypanosoma cruzi. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, v. 1867, p. 118694, 2020.
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MALVEZZI, AMARANTA MUNIZ ; ARICÓ, MIRELLA ; SOUZA-MELO, NORMANDA ; DOS SANTOS, GREGORY PEDROSO ; BITTENCOURT-CUNHA, PAULA ; HOLETZ, FABIOLA BARBIERI ; Schenkman, Sergio . GCN2-Like Kinase Modulates Stress Granule Formation During Nutritional Stress in Trypanosoma cruzi. Frontiers in Cellular and Infection Microbiology, v. 10, p. 19, 2020.
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MATUTINO BASTOS, TANIRA ; BOTELHO PEREIRA SOARES, MILENA ; HADDAD FRANCO, CAIO ; ALCÂNTARA, LAURA ; ANTONINI, LORENZO ; SABATINO, MANUELA ; MAUTONE, NICOLA ; HOLANDA FREITAS-JUNIOR, LUCIO ; MORAES, CAROLINA BORSOI ; RAGNO, RINO ; ROTILI, DANTE ; Schenkman, Sergio ; MAI, ANTONELLO ; SILVIO MORETTI, NILMAR . Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 21, p. 3659, 2020.
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MACHADO, FABRICIO CASTRO ; BITTENCOURT'CUNHA, PAULA ; MALVEZZI, AMARANTA MUNIZ ; ÁRICO, MIRELLA ; RADIO, SANTIAGO ; SMIRCICH, PABLO ; ZOLTNER, MARTIN ; FIELD, MARK C. ; Schenkman, Sergio . EIF2α phosphorylation is regulated in intracellular amastigotes for generation of infective Trypanosoma cruzi trypomastigote forms. CELLULAR MICROBIOLOGY, v. 22, p. e13243, 2020.
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FRANCO, CAIO H. ; WARHURST, DAVID C. ; BHATTACHARYYA, TAPAN ; AU, HO Y.A. ; LE, HAI ; Giardini, Miriam A. ; PASCOALINO, BRUNO S. ; TORRECILHAS, ANA CLAUDIA ; ROMERA, LAVINIA M.D. ; MADEIRA, RAFAEL PEDRO ; Schenkman, Sergio ; Freitas-Junior, Lucio H. ; CHATELAIN, ERIC ; MILES, MICHAEL A. ; MORAES, CAROLINA B. . Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity. International Journal for Parasitology-Drugs and Drug Resistance, v. 13, p. 107-120, 2020.
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OLIVEIRA, VIVIAN CRISTINA DE ; LACERDA, MARCELO PITOMBEIRA DE ; MORAES, BÁRBARA BOMFIM MUNIZ ; GOMES, CAIO PEREZ ; MARICATO, JULIANA TERZI ; SOUZA, OLIVIA FONSECA ; Schenkman, Sergio ; Pesquero, João Bosco ; MORETTI, NILMAR SILVIO ; RODRIGUES, CELSO ARRAIS ; POPI, ANA FLAVIA . Deregulation of Ikaros expression in B-1 cells: New insights in the malignant transformation to chronic lymphocytic leukemia. JOURNAL OF LEUKOCYTE BIOLOGY, v. 106, p. 581-594, 2019.
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MATUTINO BASTOS, TANIRA ; MANNOCHIO RUSSO, HELENA ; SILVIO MORETTI, NILMAR ; Schenkman, Sergio ; MARCOURT, LAURENCE ; GUPTA, MAHABIR ; WOLFENDER, JEAN-LUC ; FERREIRA QUEIROZ, EMERSON ; BOTELHO PEREIRA SOARES, MILENA . Chemical Constituents of Anacardium occidentale as Inhibitors of Trypanosoma cruzi Sirtuins. MOLECULES, v. 24, p. 1299, 2019.
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FIGUEREDO, ANDREZA S. ; DE ANDRADE, PETERSON ; RIUL, THALITA B. ; MARCHIORI, MARCELO F. ; DE LEO, THAIS CANASSA ; FLEURI, ANNA KAROLINE A. ; SCHENKMAN, SÉRGIO ; BARUFFI, MARCELO D. ; Carvalho, Ivone . Galactosyl and sialyl clusters: synthesis and evaluation against T. cruzi parasite. PURE AND APPLIED CHEMISTRY (ONLINE), v. 91, p. 1191-1207, 2019.
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MORETTI, NILMAR SILVIO ; MORTARA, RENATO ARRUDA ; Schenkman, Sergio . Trypanosoma cruzi. TRENDS IN PARASITOLOGY, v. 36, p. 404-405, 2019.
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MACHADO, FABRICIO CASTRO ; FRANCO, CAIO HADDAD ; DOS SANTOS NETO, JOSE VITORINO ; DIAS-TEIXEIRA, KARINA LUIZA ; MORAES, CAROLINA BORSOI ; LOPES, ULISSES GAZOS ; AKTAS, BERTAL HUSEYIN ; Schenkman, Sergio . Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation. Scientific Reports, v. 8, p. 4857, 2018.
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RIBEIRO, KLEBER SILVA ; VASCONCELLOS, CAMILLA IOSHIDA ; SOARES, RODRIGO PEDRO ; MENDES, MARIA TAYS ; ELLIS, CAMERON C. ; AGUILERA-FLORES, MARCELA ; DE ALMEIDA, IGOR CORREIA ; Schenkman, Sergio ; IWAI, LEO KEI ; TORRECILHAS, ANA CLAUDIA . Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells. JOURNAL OF EXTRACELLULAR VESICLES, v. 7, p. 1463779, 2018.
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MOREIRA, DOUGLAS DE SOUZA ; DUARTE, ANA PAULA ; PAIS, FABIANO SVIATOPOLK MIRSKY ; SILVA-PEREIRA, ROSIANE APARECIDA DA ; ROMANHA, ALVARO JOSÉ ; Schenkman, Sergio ; MURTA, SILVANE MARIA FONSECA . Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations. Memórias do Instituto Oswaldo Cruz, v. 113, p. e180162, 2018.
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GOMES PASSOS SILVA, DANIELLE DA SILVA SANTOS, SELMA NARDELLI, SHEILA C. MENDES, ISABELA CECÍLIA FREIRE, ANNA CLÁUDIA GUIMARÃES REPOLÊS, BRUNO MARÇAL RESENDE, BRUNO CARVALHO COSTA-SILVA, HÉLLIDA MARINA DA SILVA, VERÔNICA SANTANA OLIVEIRA, KARLA ANDRADE DE OLIVEIRA, CAMILA FRANCO BATISTA VILELA, LIZA FIGUEIREDO FELICORI NAGEM, RONALDO ALVES PINTO FRANCO, GLÓRIA REGINA Macedo, Andrea Mara Pena, Sergio Danilo Junho TAHARA, ERICH BIRELLI SALES JUNIOR, POLICARPO ADEMAR MOREIRA, DOUGLAS SOUZA Teixeira, Santuza Maria Ribeiro MCCULLOCH, RICHARD VIRGILIO, STELA TOSI, LUIZ RICARDO ORSINI Schenkman, Sergio ANDRADE, LUCIANA OLIVEIRA , et al. ; The in vivo and in vitro roles of Trypanosoma cruzi Rad51 in the repair of DNA double strand breaks and oxidative lesions. PLoS Neglected Tropical Diseases, v. 12, p. e0006875, 2018.
Schenkman, Sergio; GONZÁLEZ, JORGE . How to invade, replicate, and escape from host organisms. A challenge in defining virulence factors for parasites. Microbes and Infection, v. 14, p. 1374-1376, 2012.
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Potenza, Mariana ; Schenkman, Sergio ; LAVERRIÈRE, MARC ; TELLEZ-IÑÓN, MARÍA TERESA . Functional characterization of TcCYC2 cyclin from Trypanosoma cruzi. Experimental Parasitology, v. 132, p. 537-545, 2012.
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DC-RUBIN, SERGIO S. C.; Schenkman, Sergio . javax.xml.bind.JAXBElement@11b85d86. Cellular Microbiology (Print), v. 14, p. 1522-1530, 2012.
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Harrison, Jennifer A. ; Kartha, K. P. Ravindranathan ; Fournier, Eric J. L. ; Lowary, Todd L. ; Malet, Carles ; Nilsson, Ulf J. ; Hindsgaul, Ole ; Schenkman, S. ; Naismith, James H. ; Field, Robert A. . Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Organic & Biomolecular Chemistry, v. 9, p. 1653, 2011.
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Genovesio, Auguste ; Giardini, Miriam A. ; Kwon, Yong-Jun ; Dossin, Fernando de Macedo ; Choi, Seo Yeon ; Kim, Nam Youl ; Kim, Hi Chul ; Jung, Sung Yong ; Schenkman, S. ; Almeida, Igor C. ; Emans, Neil ; Freitas-Junior, Lucio H. . Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection. Plos One, v. 6, p. e19733, 2011.
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Ramos, Thiago Cesar Prata ; Freymüller-Haapalainen, Edna ; Schenkman, S. . Three-dimensional reconstruction of Trypanosoma cruzi epimastigotes and organelle distribution along the cell division cycle. Cytometry. Part A, v. 79A, p. 538-544, 2011.
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Gallo, Gloria ; Ramos, Thiago Cesar Prata ; Tavares, Fernanda ; Rocha, Antonio A. ; Machi, Emerson ; Schenkman, S. ; Bahia, Diana ; Pesquero, João Bosco ; Würtele, Martin . Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion. Biochemical and Biophysical Research Communications (Print), v. 408, p. 427-431, 2011.
Oliveira, Gabriel M. ; Yoshida, Nobuko ; Higa, Elisa M. S. ; Schenkman, S. ; Alves, Monique ; Staquicini, Daniela ; Cascabulho, Cynthia ; Schor, Nestor . Induction of proinflammatory cytokines and nitric oxide by Trypanosoma cruzi in renal cells. Parasitology Research (1987. Print), v. 109, p. 483-491, 2011.
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Calderano, Simone Guedes ; Diogo de Melo Godoy, Patrícia ; Motta, Maria Cristina M. ; Mortara, Renato A. ; Schenkman, Sergio ; Elias, M. Carolina . Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery. Nucleus, v. 2, p. 136-145, 2011.
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Lovato, Diogo Ventura; Amino, Rogerio; González, Yamile; Miranda, Antonio ; Schenkman, Sergio; Tanaka, Aparecida S. . Infestin 1R, an intestinal subtilisin inhibitor from Triatoma infestans able to impair mammalian cell invasion by Trypanosoma cruzi. Experimental Parasitology, v. 129, p. 362-367, 2011.
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Tonelli, Renata R. ; Augusto, Leonardo da Silva ; Castilho, Beatriz A. ; Schenkman, Sergio . Protein Synthesis Attenuation by Phosphorylation of eIF2 Is Required for the Differentiation of Trypanosoma cruzi into Infective Forms. Plos One, v. 6, p. e27904, 2011.
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Costa, F.C. ; Oliva, M.A.V.; Jesus, T. C. L. ; Schenkman, S.; Thiemann, O.H. . Oxidative stress protection of Trypanosomes requires selenophosphate synthase. Molecular and Biochemical Parasitology (Print), v. 180, p. 47-50, 2011.
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CARVALHO, I. ; ANDRADE, P. ; CAMPO, V. L. ; Guedes, Paulo M.M. ; Sesti-Costa, Renata ; Silva, João S. ; Schenkman, S. Dedola, Simone ; Hill, Lionel ; Rejzek, Martin . `Click chemistry synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase. Bioorganic & Medicinal Chemistry, v. 18, p. 2412-2427, 2010.
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Erben, Esteban D. ; Valguarnera, Ezequiel; Nardelli, Sheila ; Chung, Janete ; Daum, Sebastian ; Potenza, Mariana ; Schenkman, S. ; Téllez-Iñón, María T. . Identification of an atypical peptidyl-prolyl cis/trans isomerase from trypanosomatids?. Biochimica et Biophysica Acta. Molecular Cell Research, v. 1803, p. 1028-1037, 2010.
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De Jesus, T. C. L. ; TONELLI, R. R. ; Nardelli, S. C. ; da Silva Augusto, L. ; Motta, M. C. M. ; Girard-Dias, W. ; Miranda, K. ; ULRICH, P. ; Jimenez, V. ; BARQUILLA, A. ; Navarro, M. ; DOCAMPO, R. ; Schenkman, S. . Target of Rapamycin (TOR)-like 1 Kinase Is Involved in the Control of Polyphosphate Levels and Acidocalcisome Maintenance in Trypanosoma brucei. The Journal of Biological Chemistry (Print), v. 285, p. 24131-24140, 2010.
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Matsuo, A. L. ; Silva, L. S. ; Torrecilhas, A. C. ; PASCOALINO, B. S. ; Ramos, T. C. ; Rodrigues, E. G. ; Schenkman, S. ; Caires, A. C. F. ; TRAVASSOS, L. R. . In Vitro and In Vivo Trypanocidal Effects of the Cyclopalladated Compound 7a, a Drug Candidate for Treatment of Chagas' Disease. Antimicrobial Agents and Chemotherapy (Print), v. 54, p. 3318-3325, 2010.
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Toledo, Juliano S. ; Ferreira, Tiago R. ; Defina, Tânia P.A. ; Dossin, Fernando de M. ; Beattie, Kenneth A. ; Lamont, Douglas J. ; Cloutier, Serge ; Papadopoulou, Barbara ; Schenkman, S. ; Cruz, Angela K. . Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity. International Journal of Biochemistry & Cell Biology, p. 1661-1671, 2010.
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Motta, Maria Cristina Machado ; Catta-Preta, Carolina Moura Costa ; Schenkman, S. ; Martins, Allan Cezar de Azevedo ; Miranda, Kildare ; DE SOUZA, W. ; Elias, Maria Carolina . The Bacterium Endosymbiont of Crithidia deanei Undergoes Coordinated Division with the Host Cell Nucleus. Plos One, v. 5, p. e12415, 2010.
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Campo, V. L., Carvalho, I., Da Silva, Carlos H. T. P., Schenkman, S., Hill, Lionel, Nepogodiev, Sergey A., Field, Robert A. . Cyclooligomerisation of azido-alkyne-functionalised sugars: synthesis of 1,6-linked cyclic pseudo-galactooligosaccharides and assessment of their sialylation by Trypanosoma cruzi trans-sialidase. Chemical Science: a new journal for findings of exceptional significance from across the chemical sciences, v. 1, p. 507, 2010.
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Elias, M.C., Nardelli, S.C., Schenkman, S. (2009) Chromatin and nuclear organization in Trypanosoma cruzi. Future Microbiology 4: 1065-1074.
Martins R.M., Amino R., Daghastanli, K.R., Cuccovia, I.M., Juliano, M.A., Schenkman, S. (2008) A short proregion of trialysin, a pore-forming protein of Triatoma infestans salivary glands, controls activity by folding the N-terminal lytic motif. FEBS J, 275:994-1002.
Ferreira, L.R.P., Dossin, F.M., Ramos, T.C., Freymuller, E., Schenkman, S. (2008) Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis. Ann. Acad. Bras. Ciências, 80:157-166.
Gutiyama, L.M., da Cunha, J.P., Schenkman, S. (2008) Histone H1 of Trypanosoma cruzi is concentrated in the nucleolus region and disperses upon phosphorylation during progression to mitosis. Eukaryotic Cell. 7:560-568.
da Cunha, J.P.C.; Nakayasu, E.S.; de Almeida, I.C.; Schenkman, S. (2006) Post-translational modifications of Trypanosoma cruzi histone H4. Mol. Biochem. Parasitol. 150:268-277.
Elias; M.C.; da Cunha, J.P.C.; de Faria, F. P.; Mortara, R.A.; Freymüller, E.; Schenkman, S. (2007) Morphological events of Trypanosoma cruzi cell cycle. Protist, 148: 147-157.
Nardelli S.C.; Avila A.R.; Freund A, Motta, M.C.; Manhae, L.; de Jesus, T.C.; Schenkman, S.; Fragoso S.P.; Krieger, M.A; Goldenberg, S., Dallagiovanna, B. (2007) SSU rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi. Eukaryotic Cell, 6: 337-345.
Rubin-De-Celis, S.S.C., Uemura, H, Yoshida, N., Schenkman, S. (2006) Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole. Cellular Microbiology, 8: 1888-1898.
Kituti, C. M.; Tersariol, I. L. S.; Schenkman, S. (2006) Divalent metal requirements for catalysis and stability of the RNA triphosphatase from Trypanosoma cruzi. Mol. Biochem. Parasitol150: 83-95
da Cunha, J.P.C., Nakayasu, E.S., Elias, M.C., Pimenta, D.C, Tellez-Inon, M.T., Rojas, F., Manuel, M,. Almeida I.C, e Schenkman, S. (2005) Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle. Mol. Biochem. Parasitol. 140:75-86.
Elias, M.C.Q.B, Vargas, N. Tomazi, L., Pedroso, A., Schenkman, S. e Briones, M.R.S. (2005) Comparative analysis of genomic sequences suggests that Trypanosoma cruzi CL Brener contains two sets of non-intercalated repeats of satellite DNA that correspond to T. cruzi I and T. cruzi II types. Mol. Biochem. Parasitol. 140: 221-227.
Dossin, F.M. e Schenkman, S. (2005) Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryotic Cell. 4(5):960-70.
Elias, M.C.B., Vargas, N.S., Zingales, B., e Schenkman, S. (2003) Organization of satellite DNA in the genome of Trypanosoma cruzi. Mol. Biochem. Parasitol. 129:1-19.
Ejchel, T.F., Ramirez, M.I., Vargas, N.S., Azevedo, E.B., Elias, M.C.B., Zingales, B., e Schenkman, S. (2003) The largest subunit of the RNA polymerase II of Trypanosoma cruzi lacks the repeats in the carboxy-terminal domain and is encoded by several genes Parasitol. International . 52:243-249.
Pereira-Chioccola, V.L., Fragata-Filho, A.A., Levy, A.M.A., Rodrigues, M.M. e Schenkman, S. (2003) Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas’ disease after drug treatment Clin. Diagn. Lab. Immunol. 10:826-830.
Elias, M.C.Q.B., Porto, R.M., Faria, M. Schenkman (2003) Distinct Mechanisms Operate to Control Stage specific and Cell cycle Dependent Gene Expression in Trypanosoma cruzi in: Molecular Mechanisms in the Pathogenesis of Chagas Disease (J.M. Kelly, Ed). Eureka.com. http://www.eurekah.com/chapter/637 ISBN: 978-0-306-47849-9
Elias, M.C.B., Faria, M., Mortara, R.A., Motta, M.C.M., de Souza, W. Thiry, M. e Schenkman, S. (2002) Chromosome localization changes in the Trypanosoma cruzi interphase nucleus. Eukariotic Cell. 1:944-953.
Amino, R., Martins, R.M., Procopio, J. Hirata,.I., Juliano, M.A., Schenkman, S. (2002) Trialysin, a Novel Pore-Forming Protein from Saliva of Haematophagous Insects Activated by Limited Proteolysis. J. Biol. Chem. 22:6207-6213.
Porto, R.M., Amino, R., Elias, M.C., Faria, M., Schenkman, S. (2002) Histone H1 is phosphorylated in non-replicating and infective forms of Trypanosoma cruzi. Mol. Biochem. Parasitol. 119:265-271